Centrifugal spray dryer quality appraisal

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centrifugal spray dryer takes the synergy of high-speed centrifugal atomization and hot air convection as the core principle. By optimizing the atomizer speed, hot air temperature control and system energy efficiency ratio, it achieves instant drying of liquid materials, synergy of particle uniformity and retention rate of heat-sensitive components. It is widely used in powder preparation in the fields of food, pharmaceutical, chemical industry and environmental protection. In the dairy industry, it is used for low-temperature instant drying of milk powder; in the pharmaceutical industry, it meets the activity retention requirements of enzyme preparations and probiotics; in the field of nanomaterials, it ensures the uniformity of the particle size of nanoparticles. Compared with traditional drying equipment, centrifugal spray dryers have the characteristics of high thermal efficiency, excellent product fluidity and automatic control, and are the core equipment of powder engineering.

Zhongke Testing is a product quality appraisal service organization registered with the court. It can provide centrifugal spray dryer quality appraisal services. It has a professional appraisal team and advanced instruments and equipment to provide fair and accurate appraisal results for centrifugal spray dryer quality appraisal.

As the requirements for powder refinement increase, related quality dispute cases have increased significantly. The judicial dispute focuses on:

1, performance index dispute: excessive moisture after drying, insufficient life of the atomizer disk;

2, material defects: insufficient hardness of the atomizer impeller, deformation of the hot air distributor baffle ;

3, process problems: hot air temperature fluctuations, cyclone separator pressure drop exceeds the standard;

4, contract performance disputes: key modules (such as variable frequency atomization motor, online cleaning system) do not comply with the technical agreement.

0 Such cases require thermodynamic simulation, material failure analysis and dynamic energy efficiency testing to clarify the quality responsibility.

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centrifugal spray dryer litigation quality appraisal technical methods mainly include:

1. Appearance inspection: Check whether the model, specification, appearance, structure, etc. of the grain fan are consistent with the contract or standard requirements.

2. Performance testing: including testing of performance parameters such as air volume, wind pressure, head, etc. to verify whether the actual performance of the grain fan meets the design requirements.

3. Material testing: Conduct component analysis and strength testing on key materials of grain fans (such as impellers and casings) to verify whether the materials meet standard requirements.

4. Processing accuracy testing: Check the processing accuracy of the grain fan, such as the dynamic balance of the impeller, the sealing of the casing, etc., to evaluate the processing technology level of the equipment.

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A pharmaceutical company of the applicant signed a "Probiotic Spray Dryer Purchase Contract" with an equipment manufacturer of the respondent, agreeing that the activity retention rate is ≥90%. After being put into production, only 60% of the bacterial activity remained. The manufacturer argued that it was due to the poor heat resistance of the material.

Identification analysis results:

The quality analysis expert group discussed and comprehensively analyzed the relevant information of the "Centrifugal Spray Dryer", the contract technical agreement, the on-site investigation case materials and other data, and made the following quality analysis opinions:

The inlet temperature control deviation of the centrifugal spray dryer involved in

is ±8°C (agreed ±3°C), and the residence time in the high-temperature section exceeds the agreed value by 2 times; the atomization disk rotation speed is only 12,000rpm (agreed ≥15,000rpm), resulting in an increase in droplet size (D90=150μm>agreed 80μm); the cyclone separator efficiency is only 85% (agreed ≥95%), and the powder is heated twice.

The appraisal conclusion concluded that defects in the temperature control system and atomizer were the main causes of activity loss.

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Centrifugal spray dryer quality appraisal report should include:

1, appraisal purpose (such as activity loss attribution, performance verification) and reference standards;

2, involved equipment model, control system version, process parameters;

3, detection method and equipment clearance Single sheet (such as laser particle size analyzer, thermal imager);

4, detection data and failure correlation analysis (such as the impact of atomized particle size on activity);

05, clear quality responsibility judgment conclusion and technical basis;

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26, signature of the appraiser, thermal engineer qualification certificate and official seal of the organization.

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